A complete list of our publications can be found here: Publications


  • Phage Therapy for Limb-threatening Prosthetic Knee Klebsiella pneumoniae Infection: Case Report and In Vitro Characterization of Anti-biofilm Activity. Cano EJ, Caflisch KM, Bollyky PL, Van Belleghem JD, Patel R, Fackler J, Brownstein MJ, Horne B, Biswas, Henry M, Malagon F, Lewallen DG, Suh GA. CLINICAL INFECTIOUS DISEASES. 2020 Jul 23:ciaa705. doi: 10.1093/cid/ciaa705.  PMID: 32699879
  • A Novel Mouse Model of Chronic Suppurative Otitis Media and its Use in Preclinical Evaluation of Antibiotics. KM Khomtchouk, A Kouhi, A Xia, LA Bekale, SM Massa, JM Sweere, D Pletzer, REW Hancock, PL Bollyky, PL Santa Maria.. SCIENCE ADVANCES .14 Aug 2020: Vol. 6, no. 33, eabc1828. DOI: 10.1126/sciadv.abc1828
  • Methods for Extraction and Detection of Pf Bacteriophage DNA from the Sputum of Patients with Cystic Fibrosis. Burgener EB, Secor PR, Tracy MC, Sweere JM, Bik EM, Milla CE, Bollyky PL. PHAGE. 2020 Jun 1;1(2):100-108.doi: 10.1089/phage.2020.0003.  PMID: 32626852
  • The immune response to chronic Pseudomonas aeruginosa wound infection in immune-competent mice. JM Sweere, H Ishak, V Sunkari, MS Bach, R Manasherob, K Yadava, SM Ruppert, CK Sen, S Balaji, SG Keswani, PR Secor, and PL Bollyky ADVANCES IN WOUND CARE. 2020 Feb 1;9(2):35-47. doi: 10.1089/wound.2019.1039. PMID:31903297
  • A Delayed Inoculation Model of Chronic Pseudomonas aeruginosa Wound Infection. CR de Vries, JM Sweere, H Ishak, V Sunkari, MS Bach, R Manasherob, and PL Bollyky.  J. VIS. EXP. 2020.(156), e60599, doi:10.3791/60599
  • Pf bacteriophage and their Impact on Pseudomonas Virulence, Mammalian Immunity, and Chronic Infections. Secor PR, Burgener EB, Kinnersley M, Jennings LK, Roman-Cruz V,  Popescu M, Van Belleghem JD, Haddock N, Copeland C,  Michaels LM,  de Vries CD, Chen Q, Pourtos J,  Wheeler TJ ,Milla CE,  and Bollyky PL. FRONTIERS IN IMMUNOLOGY. 2020. 11:244. doi: 10.3389/fimmu.2020.00244
  • The Role of the Anti-Inflammatory Cytokine IL-10 in Tissue Fibrosis. E Steen, X Wang, S Balaji, MJ Butte, PL Bollyky, SG Keswani. ADVANCES IN WOUND CARE. 2020. 184-198
  • The Heparan Sulfate Mimetic PG545 polarizes T-cell responses towards Foxp3+ Treg. IO Koliesnik, HF Kuipers, CO Medina, S Zihsler, JD Van Belleghem, and PL Bollyky.  FRONTIERS IN IMMUNOLOGY. 2020 Feb 6;11:132. doi: 10.3389/fimmu.2020.00132. eCollection 2020. PMID:32117279.
  • High molecular weight hyaluronan attenuates tubulointerstitial scarring in kidney injury. Wang X, Balaji S, Steen EH, Blum AJ, Li H, Chan CK, Manson SR, Lu TC, Rae MM, Austin PF, Wight TN, Bollyky PL, Cheng J, Keswani SG. JCI INSIGHT. 2020 May 12. pii: 136345. doi: 10.1172/jci.insight.136345. PMID: 32396531
  • The Role of an IL-10/Hyaluronan Axis in Dermal Wound Healing. KL Singampalli, S Balaji, X Wang, UM Parikh, A Kaul, J Gilley, RK Birla, PL Bollyky, SG Keswani. . FRONTIERS IN CELLULAR AND DEVELOPMENTAL BIOLOLGY. 8:636. doi: 10.3389/fcell.2020.00636.


  • Filamentous Bacteriophage Suppress Clearance of Bacterial Infection. JM Sweere, J Van Bellegehem, H Ishak, MS Bach, M Popescu, V Sunkari, G Kaber, R Manasherob,GA Suh, X Cao,CR De Vries, DN Lam, PL Marshall, M Birukova, E Katznelson, DV Lazzareschi, S Balaji, S Keswani, TR Hawn, PR Secor, and PL Bollyky.. SCIENCE. (2019) 363, 6434, 1416. DOI: 10.1126/science.aat9691
  • Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in Cystic Fibrosis. EB Burgener, JM Sweere, MS Bach, PR Secor, N Haddock, LK Jennings, RL Marvig, HK Johansen, E Rossi, X Cao, L Tian, L Nedelec, S Molin, PL Bollyky* and CE Milla*  SCIENCE TRANSLATIONAL MEDICINE. 17 Apr 2019: Vol. 11, Issue 488, eaau9748 DOI: 10.1126/scitranslmed.aau9748   *co-senior authors
  • The innate sense of bacteriophages. Bollyky PL, Secor PR. CELL HOST & MICROBE. 2019 Feb 13;25(2):177-179. doi: 10.1016/j.chom.2019.01.020.
  • Perspectives of phage therapy in non-bacterial infections. Górski A, Bollyky PL, Przybylski M, Borysowski J, Międzybrodzki R, Jończyk-Matysiak E, and Weber-Dąbrowska B. FRONTIERS IN MICROBIOLOGY. 2019 Jan 9;9:3306.doi: 10.3389/fmicb.2018.03306
  • The Immune Response to Chronic Pseudomonas aeruginosa Wound Infection in Immunocompetent Mice. JM Sweere, H Ishak, V Sunkari, MS Bach, R Manasherob, K Yadava, SM Ruppert, CK Sen, S Balaji, SG Keswani, PR Secor, and PL Bollyky.  ADVANCES IN WOUND CARE.  2019 6 Aug 2019.
  • Quantitative assessment of bacterial growth phase utilizing flow cytometryKhomtchouk KM, Weglarz M, Bekale LA, Kolesnik I, Bollyky PL, Santa Maria PL.        J MICROBIOL METHODS. 2019 Oct 30:105760. doi: 10.1016/j.mimet.2019.105760.
  • T Lymphocytes Attenuate Dermal Scarring by Regulating Inflammation, Neovascularization, and Extracellular Matrix Remodeling.  X Wang, S Balaji, EH Steen, H Li, MM Rae, AJ Blum, Q Miao, MJ Butte, PL Bollyky,  SG Keswani. ADVANCES IN WOUND CARE. 2019 22 July.
  • 4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition. N Nagy, I Gurevich, HF Kuipers, SM Ruppert, PL Marshall, BJ Xie, W Sun, AV Malkovskiy, J Rajadas, M Grandoch, JW Fischer, AR Frymoyer, G Kaber, and PL Bollyky. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019 Mar 26. pii: jbc.RA118.006166. doi: 10.1074/jbc.RA118.006166.
  • 4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue. M Grandoch, U Flögel, S Virtue, JK Maier, T JelenikC Kohlmorgen, K Feldmann, Y Podsvyadek, TR. Castañeda, Z Zhou, Y Yamaguchi, EBM Nascimento, VG Sunkari, C Goy, M Kinzig, F Sörgel, PL Bollyky, P Schrauwen, H Al-Hasani, M Roden, S Keipert, A Vidal-Puig, M Jastroch, J Haendeler, JW Fischer. NATURE METABOLISM. 2019 April 22.
  • The Role of the Anti-Inflammatory Cytokine IL-10 in Tissue Fibrosis. E Steen, X Wang, S Balaji, MJ Butte, PL Bollyky, SG Keswani. ADVANCES IN WOUND CARE. 2019. Aug 30
  • Lung-resident Tr1-like cells do not confer lasting tolerance to airway allergens. K Yadava*, CO Medina*, H Ishak, I Gurevich, HF Kuipers, EA Shamskhou, JJ Moon, C Weaver, G Ogg, K Nadeau, and PL Bollyky.  eLIFE. 2019 Oct 11.  * Co-first authors.
  • Hydrogel-based delivery of IL-10 improves treatment of bleomycin-induced lung fibrosis in mice. EA Shamskhou, MJ Kratochvil, ME Orcholski, N Nagy, G Kaber, E Steen, S Balaji, SG Keswani, B Danielson, K Yuan,, PL Bollyky*, and V De Jesus Perez*. BIOMATERIALS 2019; Feb 22 203;52-62 *co-senior authors
  • Adenosine and hyaluronan modulate lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema (CPFE). Collum SD, Molina JG, Hanmandlu A, Bi W, Pedroza M, Mertens TCJ, Wareing N, Wei W, Wilson C, Sun W, Rajadas J, Bollyky PL, Philip KM, Ren D, Thandavarayan RA, Bruckner BA, Xia Y, Blackburn MR, Karmouty-Quintana H. DISEASE MODELS AND MECHANISMS. 2019 Apr 29. pii: dmm.038711. doi: 10.1242/dmm.038711.
  • Salivary thiocyanate as a biomarker of Cystic Fibrosis Transmembrane Regulator function. Malkovskiy AV, Yacob AA, Dunn CE, Zirbes JM, Ryan SP, Bollyky PL, Rajadas J, Milla CE. ANALYTICAL CHEMISTRY. 2019 May 22. doi: 10.1021/acs.analchem.9b01800


  • Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System. Van Belleghem JD, Dąbrowska K, Vaneechoutte M, Barr JJ, Bollyky PL. VIRUSES. 2018 Dec 25;11(1). pii: E10. doi: 10.3390/v11010010.
  • Macrophages and innate immune memory against Staphylococcus skin infections. Van Belleghem JD and Bollyky PL. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES.
  • Periprosthetic bacterial biofilm and quorum sensing. Mooney JA, Pridgen EM, Manasherob R, Suh G, Blackwell HE, Barron AE, Bollyky PL, Goodman SB, Amanatullah DF. JOURNAL OF ORTHOPEDIC RESEARCH. 2018 Apr 16. doi: 10.1002/jor.24019
  • Chitin, chitinases, and chitin lectins: Emerging roles in human pathophysiology. Ziatabar S, Zepf J, Rich S, Danielson BT, Bollyky PI, Stern R. PATHOPHYSIOLOGY. 2018 Mar 6. pii: S0928-4680(18)30023-3. doi: 10.1016/j.pathophys.2018.02.005.
  • Human Chitotriosidase Does Not Catabolize Hyaluronan.   B Danielson, CH Chen, G Kaber, D Mochly-Rosen, K Grimes, R Stern, PL Bollyky. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2018.
  • Hyaluronan levels are increased systemically in human type 2 but not type 1 diabetes independently of glycemic control. Nagy N, Sunkari VG, Kaber G, Hasbun S, Lam DN, Speake C, Sanda S, McLaughlin TL, Wight TN, Long SR, Bollyky PL. MATRIX BIOLOGY. 2018 Sep 6. pii: S0945-053X(18)30309-3.doi: 10.1016/j.matbio.2018.09.003.
  • Hyaluronan: A Master Switch Between Vascular Homeostasis and Inflammation. Grandoch M, Bollyky PL, Fischer JW. CIRCULATION RESEARCH. 2018 May 11;122(10):1341-1343. doi: 10.1161/CIRCRESAHA
  • Hyaluronan in immune dysregulation and autoimmune diseases. Nagy N, Kuipers HF, Marshall PL, Wang E, Kaber G, Bollyky PL. MATRIX BIOLOGY. 2018 Apr 4. pii: S0945-053X(17)30440-7. doi: 10.1016/j.matbio.2018.03.022
  • Hyaluronan content governs tissue stiffness in pancreatic islet inflammation. N Nagy, A de la Zerda, G Kaber, MJ Kratochvil, K Yadava, W Zhao, Y Cui, G Navarro, JP Annes, PY Johnson, KH Hu, CK Chan, TN Wight, SC Heilshorn, PL Bollyky*, MJ Butte*. JOURNAL OF BIOLOGICAL CHEMISTRY.  2017  *co-senior authors DOI: 10.1074/jbc.RA117.000148 
  • Hyaluronan synthase 3 promotes plaque inflammation and atheroprogression. Homann, S, Grandoch, M, Kiene, LS, Podsvyadek, Y, Feldman, K, Rabausch, B, Nagy, N, Lehr, S, Kretschmer, I, Oberhuber, A, Bollyky, PL, and Fischer, JW. MATRIX BIOLOGY. 2018.  DOI: 10.1016/j.matbio.2017.09.005
  • Extracellular matrix and the maintenance and loss of peripheral immune tolerance in autoimmune insulitis. Medina CO, Nagy N, Bollyky PL. CURRENT OPINIONS IN IMMUNOLOGY. 2018 Sep 21;55:22-30. doi: 10.1016/j.coi.2018.09.006


  • Filamentous bacteriophage produced by Pseudomonas aeruginosa alters the inflammatory response and promotes noninvasive infection In Vivo. Secor, PR, Michaels, LA, Smigiel, KS, Rohani, MG, Jennings, LK, Hisert, KB, Arrigoni, A, Braun, KR, Birkland, TP, Lai, Y, Hallstrand, TS, Bollyky, PL, Singh, PK, and WC Parks. INFECTION AND IMMUNITY. 2017.  DOI:10.1128/IAI.00648-16
  • Pseudomonas phage inhibition of Candida albicans. Nazik H, Joubert LM, Secor PR, Sweere JM, Bollyky PL, Sass G, Cegelski L, Stevens DA. MICROBIOLOGY. 2017 Nov;163(11):1568-1577. doi: 10.1099/mic.0.000539
  • Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis. Collum, SD, Chen, NY, Hernandez, AM, Hanmandlu, A, Sweeney, H, Mertens, TCJ, Weng, T, Lou, F, Molina, JG, Davies, J, Horan, IP, Morrell, NW, Amione-Guerra, J, Al-Jabbari, O, Youker, K, Sun, W, Rajadas, J, Bollyky, PL, Akkanti, BH, Jyothula, S, Sinha, N, Guha, A, and H Karmouty-Quintara. BRITISH JOURNAL OF PHARMACOLOGY. 2017. DOI: 10.1111/bph.13947
  • A consensus definitive classification of scavenger receptors and their roles in health and disease.  PrabhuDas, MR, Bladwin, CL, Bollyky, PL, Bowdish, DME, Drickamer, K, Febbaraio, M, Herz, J, Kobzik, L, Krieger, M, Loike, J, McVicker, B, Means, TK, Moestrup, SK, Post, SR, Sawamura, T, Silverstein, S, Speth, RC, Telfer, JC, Thiele, GM, Wang, XY, Wright, SD, and J El Khoury. THE JOURNAL OF IMMUNOLOGY.  2017.  DOI:
  • Regulatory and effector T-cells potentiate wound repair by regulating inflammation and extracellular matrix.   Wang, X, BBalaji, M, Rae, K, Matatall, Li, H, Sunkari, V, Duann, P, Chandramouli, King, K, Butte, M, Bollyky, P, and S Keswani.  JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017. DOI: 10.1016/j.jid.2017.02.921
  • Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination.  Kuipers, HF, Yoon, J, van Horssen, J, Han, MH, Bollyky, PL, Palmer, TD, and L Steinman.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. 2017. DOI:10.1073/pnas.1621314114
  • Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling.  Balaji, S, Wang, X, King, A, Le, LD, Bhattacharya SS, Moles, CM, Butte, MG, de Jesus Perez, VA, Liechty, KW, Wight, TN, Crombleholme, TM, Bollyky, PL, Keswani SG. FASEB JOURNAL. 2017. Nov 30 Epub. DOI: 10.1096/fj.201600856R


  • Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance.  Journal of Leukocyte Biology. Lee, HW, Jie, HB, Bollyky PL, Sarracino, D, Kim, TS, Wilson, BS. 2016; Nov 11 Epub. DOI: 10.1189/jib.1A0416-164RRR
  • Filamentous bacteriophage produced by Pseudomonas aeruginosa alters the inflammatory response and promotes non-invasive infection in vivo. INFECTION AND IMMUNOLOGY. Secor, PR, Michaels, LA, Smigiel, KS, Rohani, MG, Jennings, LK, Hisert, KB, Arrigoni, A, Braun, KR, Birkland, TP, Lai, Y, Hallstrand, TS, Bollyky, PL, Singh, PK, Parks, WC. 2016; Oct 17 Epub.  DOI: 10.1128/IAI.00648-16
  • Modified High Molecular Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance.  AMERICAN  JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. Gebe, JA, Yadava, K, Ruppert, SM, Marshall, P, Hill, P, Falk, BA, Sweere, JM, Han, H, Kaber, G, Medina, C, Mikecz, K, Ziegler, SF, Balaji, S, Keswani, SG, de Jesus Perez, VA, Butte, M.J,Nadeau, K, Altemeier, WA, Fanger, N, Bollyky, PL. 2016 Sep 6.  DOI:10.1165/rcmb.2016-0111OC
  • The phamacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice.  CLINICAL & EXPERIMENTAL IMMUNOLOGY. Kuipers, H.F., Nagy, N., Ruppert, S.M, Sunkari, VG,Marshall, PL, Gebe, JA, Ishak, HD, Keswani, SG, Bollyky, J,Frymoyer, AR, Wight, TN, Steinman, L, Bollyky, PL. 2016; 185 (3): 372-381. DOI: 10.1111/cei.12815
  • Pf4 bacteriophage produced by Pseudomonas aeruginosa inhibits Aspergillus fumigatus metabolism via iron sequestration. MICROBIOLOGY. Penner, JC., Ferreira, JA, Secor, PR, Sweere, JM, Birukova, M, Joubert, LM, Haagensen, JA, Garcia, O., Malkovskiy, AV., Kaber, G, Nazik, H., Manasherob, R, Spormann, AM, Clemons, KV., Stevens, D.A, BollykyPL. 2016 [Epub ahead of print]  DOI: 10.1099/mic.0.000344
  • The formation and function of tertiary lymphoid follicles in chronic pulmonary inflammation.  IMMUNOLOGY.  Yadava, KY, Bollyky, PL, Lawson, MA. 2016. [Epub ahead of print] DOI: 10.1111/imm.12649
  • Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. Kuipers, HF, Rieck, M, Gurevich, I, Nagy, N., Butte, MJ,Negrin, RS, Wight, TN, Steinman, L, Bollyky, PL. 2016. DOI: 10.1073/pnas.1525086113


  • Biofilm assembly becomes crystal clear- filamentous bacteriophage organize the Pseudomonas aeruginosa biofilm matrix into a liquid crystal.  MICROBIAL CELL. Secor, PR, Jennings, LK, Michaels, LA, Sweere, JM, Singh, PK, Parks, WC, Bollyky, PL 2015. 3; 1, 49-52.  DOI: 10.15698/mic2016.01.475
  • Filamentous Bacteriophage Promote Biofilm Assembly and Function. CELL HOST & MICROBE. Secor, PR, Sweere, JM, Michaels, LA, Malkovskiy, AV, Lazzareschi, D, Katznelson, E, Rajadas, J, Birnbaum, ME, Arrigoni, A, Braun, KR, Evanko, SP, Stevens, DA, Kaminsky, W, Singh, PK, Parks, WC, Bollyky, PL.  2015; 18;5, 549-559. DOI 10.1016/Jchom.2015.10.013
  • Chemokine Involvement in Fetal and Adult Wound Healing.  ADVANCES IN WOUND CARE.  Balaji, S, Watson, CL, Ranjan, R, King, A, Bollyky, PL, Keswani, SG 2015; 4 (11):660-672.  PMID:26543680
  • Inhibition of hyaluronan synthesis restores immune tolerance during autioimmune insulitis.  JOURNAL OF CLINICAL INVESTIGATION Nagy, N, Kaber, G, Johnson, PY, Gebe, JA, Preisinger, A, Falk, BA, Sunkari, VG, Gooden, MD, Vernon, RB, Bogdani, M, Kuipers, HF, Day, AJ, Campbell, DJ, Wight, TN, Bollyky, PL. 2015 DOI 10.1172/JCI79271
  • The role of interleukin-10 and hyaluronan in murine fetal fibroblast function in vitro: implications for recapitulating fetal regenerative wound healing. PLoS ONE.  Balaji, S, King, A, Marsh, E, LeSaint, M, Bhattacharya, SS, Han, N, Dhamija ,Y, Ranjan, R, Le, LD, Bollyky, PL, Crombleholme, TM, Keswani, SG. 2015; 10(5):e0124302. DOI 10.1371/journal.pone.0124302
  • Angiopoietin-1 improves endothelial progenitor cell-dependent neovascularization in diabetic wounds. SURGERY.  Balaji, S, Han N, Moles C., Shaaban AF, Bollyky PL, Crombleholme TM, Keswani SG. 2015; 158(3): 846-856.  DOI 10.1016/Jsurg.2015.06.034
  • Regulatory T cells resist cyclosporine-induced cell death via CD44-mediated signaling pathways.  INTERNATIONAL JOURNAL OF CELL BIOLOGY Ruppert, SM, Falk, BA, Long, SA, Bollyky, PL. 2015 DOI 10.1155/2015/614297
  • 4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and canceR FRONTIERS IN IMMUNOLOGY  Nagy, N, Kuipers, HK, Frymoyer, AR, Ishak, HD, Bollyky, JB, Wight, TN, Bollyky, PL. 2015; 6: 123. DOI 10.3389/fimmu.2015.00123 


  • Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis. DIABETES.  Bogdani, M, Johnson, PY, Potter-Perigo, S, Nagy, N, Day, AJ, Bollyky, PL, Wight, TN. 2014; 63 (8): 2727-2743    DOI 10.2337/db13-1658
  • Adenoviral-mediated gene transfer of insulin-like growth factor 1 enhances wound healing and induces angiogenesis. JOURNAL OF SURGICAL RESEARCH.  Balaji, S, LeSaint, M, Bhattacharya, SS, Moles, C, Dhamija, Y, Kidd, M, Le, LD, King, A, Shaaban, A, Crombleholme, TM, Bollyky, P, Keswani, SG. 2014; 190 (1): 367-377 DOI 10.1016/Jjss.2014.02.051
  • Comparison of interleukin 10 homologs on dermal wound healing using a novel human skin ex vivo organ culture model. JOURNAL OF SURGICAL RESEARCH. Balaji, S, Moles, CM, Bhattacharya, SS, LeSaint, M, Dhamija, Y, Le, LD, King, A, Kidd, M, Bouso, MF, Shaaban, A, Crombleholme, TM, Bollyky, P, Keswani, SG. 2014; 190 (1): 358-366  DOI 10.1016/Jjss.2014.02.027
  • Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation. IMMUNOLOGIC RESEARCH Ruppert, SM, Hawn, TR, Arrigoni, A, Wight, TN, Bollyky, PL. 2014; 58 (2-3): 186-192  DOI 10.1007/s12026-014-8495-2


  • Evaluation of in vivo T cell kinetics: use of heavy isotope labeling in type 1 diabetes. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Bollyky, J B, Long, SA, Fitch, M, Bollyky, PL, Rieck, M, Rogers, R, Samuels, PL, Sanda, S, Buckner, JH, Hellerstein, MK, Greenbaum, CJ. 2013; 172 (3): 363-374  DOI 10.1111/cei.12064
  • IL-10 Induction from Implants Delivering Pancreatic Islets and Hyaluronan. JOURNAL OF DIABETES RESEARCHBollyky, PL, Vernon, RB, Falk, BA, Preisinger, A, Gooden, MD, Nepom, GT, Gebe, JA. 2013  DOI 10.1155/2013/342479


  • Science and government. Obama and the promotion of international science. SCIENCEBollyky, TJ, Bollyky, PL. 2012; 338 (6107): 610-612  DOI 10.1126/science.1230970
  • The Role of Hyaluronan and the Extracellular Matrix in Islet Inflammation and Immune Regulation. CURRENT DIABETES REPORTSBollyky, PL, Bogdani, M, Bollyky, JB, Hull, RL, Wight, TN. 2012; 12 (5): 471-480  DOI 10.1007/s11892-012-0297-0
  • Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration. MATRIX BIOLOGY. Evanko, SP, Potter-Perigo, S, Bollyky, PL, Nepom, GT, Wight, TN. 2012; 31 (2): 90-100  DOI 10.1016/Jmatbio.2011.10.004
  • Reversal of Diabetes in Mice With a Bioengineered Islet Implant Incorporating a Type I Collagen Hydrogel and Sustained Release of Vascular Endothelial Growth Factor. CELL TRANSPLANTATION. Vernon, RB, Preisinger, A, Gooden, MD, D’Amico, LA, Yue, BB, Bollyky, PL, Kuhr, CS, Hefty, TR, Nepom, GT, Gebe, JA. 2012; 21 (10): 2099-2110.  DOI 10.3727/096368912X636786


  • Low-Dose Antigen Promotes Induction of FOXP3 in Human CD4(+) T Cells. JOURNAL OF IMMUNOLOGY. Long, SA, Rieck, M, Tatum, M, Bollyky, PL, Wu, RP, Muller, I, Ho, J, Shilling, HG, Buckner, JH. 2011; 187 (7): 3511-3520.  DOI 10.4049/jimmunol.1003880
  • ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES Bollyky, PL, Wu, RP, Falk, BA, Lord, J D., Long, SA, Preisinger, A, Teng, B., Holt, GE, Standifer, NE, Braun, KR, Xie, C. F., Samuels, PL, Vernon, RB,Gebe, JA, Wight, TN, Nepom, GT 2011; 108 (19): 7938-7943.   DOI 10.1073/pnas.1017360108
  • Isolated Infection of a Decommissioned Penile Prosthesis Reservoir with Actinomyces neuii. JOURNAL OF SEXUAL MEDICINE. Hsi, RS, Hotaling, J M, Spencer, ES, Bollyky, PL, Walsh, TJ. 2011; 8 (3): 923-926.   DOI 10.1111/J1743-6109.2010.02144.x


  • Peptide-MHC Cellular Microarray with Innovative Data Analysis System for Simultaneously Detecting Multiple CD4 T-Cell Responses. PLOS ONE. Ge, X, Gebe, JA, Bollyky, PL, James, EA, Yang, J, Stern, LJ ,Kwok, WW. 2010; 5 (6)  DOI 10.1371/journal.pone.0011355
  • Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse. CELLULAR & MOLECULAR IMMUNOLOGY. Bollyky, PL, Evanko, SP, Wu, RP, Potter-Perigo, S, Long, SA, Kinsella, B, Reijonen, H, Guebtner, K, Teng, B, Chan, CK, Braun, KR, Gebe, JA, Nepom, GT, Wight, TN. 2010; 7 (3): 211-220.  DOI 10.1038/cmi.2010.9
  • Assessment of Seasonal Influenza A Virus-Specific CD4 T-Cell Responses to 2009 Pandemic H1N1 Swine-Origin Influenza A Virus. JOURNAL OF VIROLOGY. Ge, X, Tan, V, Bollyky, PL, Standifer, NE, James, EA, Kwok, WW. 2010; 84 (7): 3312-3319.  DOI 10.1128/JVI.02226-09
  • Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4(+) CD25(+) Regulatory T-Cells of Type 1 Diabetic Subjects. DIABETES. Long, SA, Cerosaletti, K, Bollyky, PL, Tatum, M, Shilling, H, Zhang, S, Zhang, Z, Pihoker, C, Sanda, S, Greenbaum, C, Buckner, JH. 2010; 59 (2): 407-415.  DOI 10.2337/db09-0694


  • Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+regulatory T cells. JOURNAL OF LEUKOCYTE BIOLOGY. Bollyky, PL, Falk, BA, Wu, RP, Buckner, JH, Wight, TN, Nepom, GT. 2009; 86 (3): 567-572.  DOI 10.1189/jlb.0109001
  • CD44 Costimulation Promotes FoxP3(+) Regulatory T Cell Persistence and Function via Production of IL-2, IL-10, and TGF-beta. JOURNAL OF IMMUNOLOGY. Bollyky, PL, Falk, BA, Long, SA, Preisinger, A, Braun, KR, Wu, RP, Evanko, SP, Buckner, JH, Wight, TN, Nepom, GT. 2009; 183 (4): 2232-2241.  DOI 10.4049/jimmunol.0900191
  • The Toll-Like Receptor Signaling Molecule Myd88 Contributes to Pancreatic Beta-Cell Homeostasis in Response to Injury. PLOS ONE. Bollyky, PL, Bice, JB, Sweet, IR, Falk, BA, Gebe, JA, Clark, AE, Gersuk, VH, Aderem, A, Hawn, TR, Nepom, GT. 2009; 4 (4).   DOI 10.1371/journal.pone.0005063

1996 – 2007

  • Cutting edge: High molecular weight hyaluronan promotes the suppressive effects of CD4(+)CD25(+) regulatory T cells. JOURNAL OF IMMUNOLOGY. Bollyky, PL, Lord, JD, Masewicz, SA, Evanko, SP, Buckner, JH, Wight, TN, Nepom, GT. 2007; 179 (2): 744-747.
  • Histoplasmosis presenting as an isolated spinal cord lesion. ARCHIVES OF NEUROLOGY. Bollyky, PL, Czartoski, TJ, Limaye, A. 2006; 63 (12): 1802-1803.
  • CD1d-restricted T-cell subsets and dendritic cell function in autoimmunity. IMMUNOLOGY AND CELL BIOLOGY. Bollyky, PL, Wilson, SB. 2004; 82 (3): 307-314  DOI 10.1111/J1440-1711.2004.01253.x
  • Multiple differences in gene expression in regulatory V alpha 24JAlpha Q T cells from identical twins discordant for type 1 diabetes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. Wilson, SB, Kent, SC, Horton, HF, Hill, AA, Bollyky, PL, Hafler, DA, Strominger, JL, Byrne, MC. 2000; 97 (13): 7411-7416.  PubMedID 10840051
  • Reconstructing the complex evolutionary history of hepatitis B virus. JOURNAL OF MOLECULAR EVOLUTION. Bollyky, PL, Holmes, EC. 1999; 49 (1): 130-141.  PubMedID 10368441
  • Recombination between sequences of hepatitis B virus from different genotypes. JOURNAL OF MOLECULAR EVOLUTION. Bollyky, PL, Rambaut, A, Harvey, PH, Holmes, EC. 1996; 42 (2): 97-102.
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