Nadine Nagy, Gernot Kaber, Mike Kratochvil and Koshika Yadava recent ly published their work entitled “Hyaluronan content governs tissue stiffness in pancreatic islet inflammation” in the Journal of Biological Chemistry. This study is the first to measure the mechanical properties of an inflamed tissue and the first to link changes in tissue stiffness to hyaluronan content. Because tissue stiffness impacts insulin production by Beta cells, these findings may help explain how islet inflammation impacts glycemic control.
Gernot Kaber, a Research Associate in the Bollyky Lab, recently won the Immunology Department’s Award for Mentor of the Year. Gernot is a devoted and patient teacher, a talented molecular biologist, and a jack-of-all-trades who keeps the lab (and most of our equipment!) running. Gernot is the person who everyone goes to when they’re wondering what to try next. Congratulations Gernot on a well-deserved award!!!
The Bollyky Lab, together with our collaborators at the Ohio State University, the University of Montana, and Texas Children’s Hospital, was recently awarded a grant to develop novel therapies against Pseudomonas aeruginosa biofilm infections of diabetic wounds.
Esther Wang was a go-getter and contacted us about a summer position in early 2017. We were impressed by her previous lab experience and were excited to have her join us. Esther has worked closely with Payton Marshall and Gernot Kaber. Payton forced her into becoming a morning person and she has spent countless hours in the TC room.
Current School/Year: Sophomore at the University of Chicago
Career Goals: MD or MD-PhD
One or MORE fun things you’ll remember about the lab:
” 1) When someone asks you to aliquot the BME, say no. (Also, don’t use a stripette, sterilize it AFTER you dilute it to minimize the smell, and, no matter what, do NOT do it in the tissue culture room.)
2) If anything goes wrong, ask Gernot. He’ll know what to do 99.9% of the time. (Just give up in the case of the other 0.1%).
3) No one ages (appearance-wise) past 20 in this lab, apparently.”
Photo: Esther in her native habitat.
Current school/year: Senior at Henry M. Gunn High School
Career Goals/ Ideas: “research scientist, reptile breeder and musician on the side.”
One OR MORE fun things about working in the Bollyky lab :
“Working on analyzing Payton’s images of dendritic cells and t-cells when exposed to heparinase and hyaluronan taught me techniques to learn and apply concepts on my own to perform a task. I will remember the moment when I finally figured out the analyzing the images of the different wells – it is very satisfying to have made a streamlined process from knowledge I gathered working with Graham.
I will remember when we went jumping because I had a great time. I really enjoyed talking with other lab members because they all had many interesting things to share. I will also remember going to Ike’s because their sandwiches are really good. I loved worked working on experiments with Heather, Gernot, and Hedwich and I got a lot more proficient with equipment and essential procedures. ” – Jerry
Photos: Taken at our Sky High Sports Trampoline jumping summer excursion.